home *** CD-ROM | disk | FTP | other *** search
| Unknown | 1992-06-06 | 352.6 KB |
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MacOS 8.1
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Win98
|
DOS
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| Confidence | Program | Detection | Match Type | Support
|
|---|
| 66%
| dexvert
| OS/2 Installation Package (archive/os2InstallPackage)
| ext
| Supported |
| 1%
| dexvert
| BeOS Installation Package (archive/beOSInstallPackage)
| ext
| Unsupported |
| 1%
| dexvert
| Newton Package (archive/newtonPackage)
| ext
| Unsupported |
| 1%
| dexvert
| Independence War 2 mod Package (other/independenceWar2ModPackage)
| ext
| Unsupported |
| 100%
| file
| data
| default
|
|
hex view+--------+-------------------------+-------------------------+--------+--------+
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|00000520| 00 00 00 01 74 13 05 00 | 1d 0d 00 00 39 34 00 00 |....t...|....94..|
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|00000550| 05 00 f4 13 00 00 39 37 | 00 00 00 01 4d 4d 05 00 |......97|....MM..|
|00000560| 48 0e 00 00 39 38 00 00 | 00 01 95 5b 05 00 c9 14 |H...98..|...[....|
|00000570| 00 00 39 39 00 00 00 01 | 5e 70 05 00 0b 12 00 00 |..99....|^p......|
|00000580| 00 00 00 00 00 00 69 82 | 05 00 00 00 00 00 24 55 |......i.|......$U|
|00000590| 6e 69 71 75 65 5f 49 44 | 7b 59 52 42 30 35 39 30 |nique_ID|{YRB0590|
|000005a0| 30 7d 0d 0a 24 54 69 74 | 6c 65 7b 4d 79 6f 63 61 |0}..$Tit|le{Myoca|
|000005b0| 72 64 69 61 6c 20 4f 78 | 79 67 65 6e 20 44 65 6c |rdial Ox|ygen Del|
|000005c0| 69 76 65 72 79 2f 43 6f | 6e 73 75 6d 70 74 69 6f |ivery/Co|nsumptio|
|000005d0| 6e 20 44 75 72 69 6e 67 | 20 43 61 72 64 69 6f 70 |n During| Cardiop|
|000005e0| 75 6c 6d 6f 6e 61 72 79 | 20 52 65 73 75 73 63 69 |ulmonary| Resusci|
|000005f0| 74 61 74 69 6f 6e 3a 20 | 20 41 20 43 6f 6d 70 61 |tation: | A Compa|
|00000600| 72 69 73 6f 6e 20 6f 66 | 20 45 70 69 6e 65 70 68 |rison of| Epineph|
|00000610| 72 69 6e 65 20 61 6e 64 | 20 50 68 65 6e 79 6c 65 |rine and| Phenyle|
|00000620| 70 68 72 69 6e 65 7d 0d | 0a 24 41 75 74 68 6f 72 |phrine}.|.$Author|
|00000630| 7b 0d 0a 42 72 6f 77 6e | 2c 20 43 47 0d 0a 54 61 |{..Brown|, CG..Ta|
|00000640| 79 6c 6f 72 2c 20 52 42 | 0d 0a 57 65 72 6d 61 6e |ylor, RB|..Werman|
|00000650| 2c 20 48 41 0d 0a 4c 75 | 75 2c 20 54 0d 0a 41 73 |, HA..Lu|u, T..As|
|00000660| 68 74 6f 6e 2c 20 4a 0d | 0a 48 61 6d 6c 69 6e 2c |hton, J.|.Hamlin,|
|00000670| 20 52 4c 7d 0d 0a 24 41 | 66 66 69 6c 69 61 74 69 | RL}..$A|ffiliati|
|00000680| 6f 6e 7b 4f 68 69 6f 20 | 53 74 61 74 65 20 55 6e |on{Ohio |State Un|
|00000690| 69 76 2c 20 43 6f 6c 75 | 6d 62 75 73 7d 0d 0a 24 |iv, Colu|mbus}..$|
|000006a0| 4a 6f 75 72 6e 61 6c 7b | 41 6e 6e 20 45 6d 65 72 |Journal{|Ann Emer|
|000006b0| 67 20 4d 65 64 7d 0d 0a | 24 53 75 62 6a 65 63 74 |g Med}..|$Subject|
|000006c0| 7b 50 68 65 6e 79 6c 65 | 70 68 72 69 6e 65 20 65 |{Phenyle|phrine e|
|000006d0| 66 66 65 63 74 73 20 6f | 6e 20 6d 79 6f 63 61 72 |ffects o|n myocar|
|000006e0| 64 69 61 6c 20 6f 78 79 | 67 65 6e 20 64 65 6c 69 |dial oxy|gen deli|
|000006f0| 76 65 72 79 2f 63 6f 6e | 73 75 6d 70 74 69 6f 6e |very/con|sumption|
|00000700| 3b 0d 0a 4d 79 6f 63 61 | 72 64 69 61 6c 20 6f 78 |;..Myoca|rdial ox|
|00000710| 79 67 65 6e 20 64 65 6c | 69 76 65 72 79 2f 63 6f |ygen del|ivery/co|
|00000720| 6e 73 75 6d 70 74 69 6f | 6e 20 64 75 72 69 6e 67 |nsumptio|n during|
|00000730| 20 43 50 52 20 28 69 6e | 20 70 69 67 29 3b 0d 0a | CPR (in| pig);..|
|00000740| 45 70 69 6e 65 70 68 72 | 69 6e 65 20 65 66 66 65 |Epinephr|ine effe|
|00000750| 63 74 73 20 6f 6e 20 6d | 79 6f 63 61 72 64 69 61 |cts on m|yocardia|
|00000760| 6c 20 6f 78 79 67 65 6e | 20 64 65 6c 69 76 65 72 |l oxygen| deliver|
|00000770| 79 2f 63 6f 6e 73 75 6d | 70 74 69 6f 6e 0d 0a 24 |y/consum|ption..$|
|00000780| 56 6f 6c 75 6d 65 7b 31 | 37 7d 0d 0a 24 50 61 67 |Volume{1|7}..$Pag|
|00000790| 65 7b 33 30 32 2d 33 30 | 38 7d 0d 0a 24 44 61 74 |e{302-30|8}..$Dat|
|000007a0| 65 7b 41 70 72 69 6c 20 | 31 39 38 38 7d 0d 0a 24 |e{April |1988}..$|
|000007b0| 59 42 56 6f 6c 7b 31 39 | 38 39 20 59 65 61 72 20 |YBVol{19|89 Year |
|000007c0| 42 6f 6f 6b 20 6f 66 20 | 45 6d 65 72 67 65 6e 63 |Book of |Emergenc|
|000007d0| 79 20 4d 65 64 69 63 69 | 6e 65 7d 0d 0a 24 43 68 |y Medici|ne}..$Ch|
|000007e0| 61 70 74 65 72 7b 31 2d | 31 7d 0d 0a 24 59 42 45 |apter{1-|1}..$YBE|
|000007f0| 64 69 74 6f 72 7b 44 72 | 2e 20 57 61 67 6e 65 72 |ditor{Dr|. Wagner|
|00000800| 7d 0d 0a 24 54 61 62 6c | 65 7b 7d 0d 0a 24 43 6f |}..$Tabl|e{}..$Co|
|00000810| 6d 6d 65 6e 74 61 74 6f | 72 7b 45 2e 48 2e 20 54 |mmentato|r{E.H. T|
|00000820| 61 6c 61 66 69 65 72 72 | 6f 2c 20 4d 2e 44 2e 7d |alafierr|o, M.D.}|
|00000830| 0d 0a 0d 0a 43 6f 70 79 | 72 69 67 68 74 20 28 63 |....Copy|right (c|
|00000840| 29 20 59 65 61 72 20 42 | 6f 6f 6b 20 4d 65 64 69 |) Year B|ook Medi|
|00000850| 63 61 6c 20 50 75 62 6c | 69 73 68 65 72 73 2c 20 |cal Publ|ishers, |
|00000860| 49 6e 63 2e 2c 20 31 39 | 38 39 0d 0a 0d 0a 31 39 |Inc., 19|89....19|
|00000870| 38 39 20 59 65 61 72 20 | 42 6f 6f 6b 20 6f 66 20 |89 Year |Book of |
|00000880| 45 6d 65 72 67 65 6e 63 | 79 20 4d 65 64 69 63 69 |Emergenc|y Medici|
|00000890| 6e 65 20 28 52 29 0d 0a | 0d 0a 43 68 61 70 74 65 |ne (R)..|..Chapte|
|000008a0| 72 20 31 2d 2d 41 63 75 | 74 65 20 53 79 73 74 65 |r 1--Acu|te Syste|
|000008b0| 6d 73 20 50 61 74 68 6f | 70 68 79 73 69 6f 6c 6f |ms Patho|physiolo|
|000008c0| 67 79 0d 0a 0d 0a 52 65 | 73 75 73 63 69 74 61 74 |gy....Re|suscitat|
|000008d0| 69 6f 6e 0d 0a 0d 0a 2d | 2d 2d 2d 2d 2d 2d 2d 2d |ion....-|--------|
|000008e0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000008f0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000900| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000910| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000920| 2d 2d 2d 2d 2d 2d 2d 0d | 0a 4d 79 6f 63 61 72 64 |-------.|.Myocard|
|00000930| 69 61 6c 20 4f 78 79 67 | 65 6e 20 44 65 6c 69 76 |ial Oxyg|en Deliv|
|00000940| 65 72 79 2f 43 6f 6e 73 | 75 6d 70 74 69 6f 6e 20 |ery/Cons|umption |
|00000950| 44 75 72 69 6e 67 20 43 | 61 72 64 69 6f 70 75 6c |During C|ardiopul|
|00000960| 6d 6f 6e 61 72 79 20 52 | 65 73 75 73 63 69 74 61 |monary R|esuscita|
|00000970| 74 69 6f 6e 3a 20 20 41 | 0d 0a 43 6f 6d 70 61 72 |tion: A|..Compar|
|00000980| 69 73 6f 6e 20 6f 66 20 | 45 70 69 6e 65 70 68 72 |ison of |Epinephr|
|00000990| 69 6e 65 20 61 6e 64 20 | 50 68 65 6e 79 6c 65 70 |ine and |Phenylep|
|000009a0| 68 72 69 6e 65 0d 0a 0d | 0a 42 72 6f 77 6e 20 43 |hrine...|.Brown C|
|000009b0| 47 2c 20 54 61 79 6c 6f | 72 20 52 42 2c 20 57 65 |G, Taylo|r RB, We|
|000009c0| 72 6d 61 6e 20 48 41 20 | 4c 75 75 20 54 2c 20 41 |rman HA |Luu T, A|
|000009d0| 73 68 74 6f 6e 20 4a 2c | 20 48 61 6d 6c 69 6e 20 |shton J,| Hamlin |
|000009e0| 52 4c 0d 0a 28 4f 68 69 | 6f 20 53 74 61 74 65 20 |RL..(Ohi|o State |
|000009f0| 55 6e 69 76 2c 20 43 6f | 6c 75 6d 62 75 73 29 0d |Univ, Co|lumbus).|
|00000a00| 0a 41 6e 6e 20 45 6d 65 | 72 67 20 4d 65 64 20 31 |.Ann Eme|rg Med 1|
|00000a10| 37 3a 33 30 32 2d 33 30 | 38 2c 20 41 70 72 69 6c |7:302-30|8, April|
|00000a20| 20 31 39 38 38 0d 0a 2d | 2d 2d 2d 2d 2d 2d 2d 2d | 1988..-|--------|
|00000a30| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a40| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a50| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a60| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a70| 2d 2d 2d 2d 2d 2d 2d 0d | 0a 0d 0a 41 62 73 74 72 |-------.|...Abstr|
|00000a80| 61 63 74 0d 0a 0d 0a 20 | 20 20 20 20 45 70 69 6e |act.... | Epin|
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|00000aa0| 61 73 6f 70 72 65 73 73 | 6f 72 20 61 67 65 6e 74 |asopress|or agent|
|00000ab0| 20 6f 66 20 63 68 6f 69 | 63 65 20 66 6f 72 20 63 | of choi|ce for c|
|00000ac0| 61 72 64 69 61 63 20 72 | 65 73 75 73 63 69 74 61 |ardiac r|esuscita|
|00000ad0| 74 69 6f 6e 2e 0d 0a 49 | 74 73 20 61 6c 70 68 61 |tion...I|ts alpha|
|00000ae0| 2d 61 64 72 65 6e 65 72 | 67 69 63 2e 20 70 72 6f |-adrener|gic. pro|
|00000af0| 70 65 72 74 69 65 73 20 | 61 72 65 20 72 65 73 70 |perties |are resp|
|00000b00| 6f 6e 73 69 62 6c 65 20 | 66 6f 72 20 69 74 73 20 |onsible |for its |
|00000b10| 62 65 6e 65 66 69 63 69 | 61 6c 20 65 66 66 65 63 |benefici|al effec|
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|00000b50| 68 65 20 6f 74 68 65 72 | 20 68 61 6e 64 2c 20 6d |he other| hand, m|
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|00000b70| 0d 0a 63 61 72 64 69 61 | 63 20 61 72 72 65 73 74 |..cardia|c arrest|
|00000b80| 2e 20 20 54 68 75 73 20 | 61 20 70 75 72 65 20 61 |. Thus |a pure a|
|00000b90| 6c 70 68 61 2d 61 67 6f | 6e 69 73 74 20 6d 61 79 |lpha-ago|nist may|
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|00000bf0| 66 65 63 74 20 6f 66 20 | 68 69 67 68 2d 64 6f 73 |fect of |high-dos|
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|00000c40| 68 72 69 6e 65 20 6f 6e | 20 72 65 67 69 6f 6e 61 |hrine on| regiona|
|00000c50| 6c 20 6d 79 6f 63 61 72 | 64 69 61 6c 0d 0a 62 6c |l myocar|dial..bl|
|00000c60| 6f 6f 64 20 66 6c 6f 77 | 2c 20 6d 79 6f 63 61 72 |ood flow|, myocar|
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|00000c90| 63 61 72 64 69 61 6c 20 | 6f 78 79 67 65 6e 20 63 |cardial |oxygen c|
|00000ca0| 6f 6e 73 75 6d 70 74 69 | 6f 6e 0d 0a 4d 56 4f 32 |onsumpti|on..MVO2|
|00000cb0| 2c 20 61 6e 64 20 64 65 | 66 69 62 72 69 6c 6c 61 |, and de|fibrilla|
|00000cc0| 74 69 6f 6e 20 72 61 74 | 65 73 20 64 75 72 69 6e |tion rat|es durin|
|00000cd0| 67 20 43 50 52 2e 0d 0a | 20 20 20 20 20 46 69 66 |g CPR...| Fif|
|00000ce0| 74 65 65 6e 20 73 77 69 | 6e 65 20 77 65 69 67 68 |teen swi|ne weigh|
|00000cf0| 69 6e 67 20 6d 6f 72 65 | 20 74 68 61 6e 20 31 35 |ing more| than 15|
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|00000d30| 6f 63 61 72 64 69 61 6c | 20 62 6c 6f 6f 64 20 66 |ocardial| blood f|
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|00001b10| 2c 20 4d 2e 44 2e 7d 0d | 0a 0d 0a 43 6f 70 79 72 |, M.D.}.|...Copyr|
|00001b20| 69 67 68 74 20 28 63 29 | 20 59 65 61 72 20 42 6f |ight (c)| Year Bo|
|00001b30| 6f 6b 20 4d 65 64 69 63 | 61 6c 20 50 75 62 6c 69 |ok Medic|al Publi|
|00001b40| 73 68 65 72 73 2c 20 49 | 6e 63 2e 2c 20 31 39 38 |shers, I|nc., 198|
|00001b50| 39 0d 0a 0d 0a 31 39 38 | 39 20 59 65 61 72 20 42 |9....198|9 Year B|
|00001b60| 6f 6f 6b 20 6f 66 20 45 | 6d 65 72 67 65 6e 63 79 |ook of E|mergency|
|00001b70| 20 4d 65 64 69 63 69 6e | 65 20 28 52 29 0d 0a 0d | Medicin|e (R)...|
|00001b80| 0a 43 68 61 70 74 65 72 | 20 31 2d 2d 41 63 75 74 |.Chapter| 1--Acut|
|00001b90| 65 20 53 79 73 74 65 6d | 73 20 50 61 74 68 6f 70 |e System|s Pathop|
|00001ba0| 68 79 73 69 6f 6c 6f 67 | 79 0d 0a 0d 0a 52 65 73 |hysiolog|y....Res|
|00001bb0| 75 73 63 69 74 61 74 69 | 6f 6e 0d 0a 0d 0a 2d 2d |uscitati|on....--|
|00001bc0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001bd0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001be0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001bf0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001c00| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 0d 0a |--------|------..|
|00001c10| 43 6f 6d 70 61 72 69 73 | 6f 6e 20 6f 66 20 45 6e |Comparis|on of En|
|00001c20| 64 6f 74 72 61 63 68 65 | 61 6c 20 61 6e 64 20 50 |dotrache|al and P|
|00001c30| 65 72 69 70 68 65 72 61 | 6c 20 49 6e 74 72 61 76 |eriphera|l Intrav|
|00001c40| 65 6e 6f 75 73 20 41 64 | 72 65 6e 61 6c 69 6e 65 |enous Ad|renaline|
|00001c50| 20 69 6e 20 43 61 72 64 | 69 61 63 0d 0a 41 72 72 | in Card|iac..Arr|
|00001c60| 65 73 74 3a 20 20 49 73 | 20 74 68 65 20 45 6e 64 |est: Is| the End|
|00001c70| 6f 74 72 61 63 68 65 61 | 6c 20 52 6f 75 74 65 20 |otrachea|l Route |
|00001c80| 52 65 6c 69 61 62 6c 65 | 3f 0d 0a 0d 0a 51 75 69 |Reliable|?....Qui|
|00001c90| 6e 74 6f 6e 20 44 4e 2c | 20 4f 27 42 79 72 6e 65 |nton DN,| O'Byrne|
|00001ca0| 20 47 2c 20 41 69 74 6b | 65 6e 68 65 61 64 20 41 | G, Aitk|enhead A|
|00001cb0| 52 0d 0a 28 4c 65 69 63 | 65 73 74 65 72 20 52 6f |R..(Leic|ester Ro|
|00001cc0| 79 61 6c 20 49 6e 66 69 | 72 6d 61 72 79 2c 20 4c |yal Infi|rmary, L|
|00001cd0| 65 69 63 65 73 74 65 72 | 2c 20 45 6e 67 6c 61 6e |eicester|, Englan|
|00001ce0| 64 29 0d 0a 4c 61 6e 63 | 65 74 20 31 3a 38 32 38 |d)..Lanc|et 1:828|
|00001cf0| 2d 38 32 39 2c 20 41 70 | 72 20 31 31 2c 20 31 39 |-829, Ap|r 11, 19|
|00001d00| 38 37 0d 0a 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |87..----|--------|
|00001d10| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001d20| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001d30| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001d40| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00001d50| 2d 2d 2d 2d 0d 0a 0d 0a | 41 62 73 74 72 61 63 74 |----....|Abstract|
|00001d60| 0d 0a 0d 0a 20 20 20 20 | 20 54 68 65 20 65 66 66 |.... | The eff|
|00001d70| 69 63 61 63 79 20 6f 66 | 20 65 6e 64 6f 74 72 61 |icacy of| endotra|
|00001d80| 63 68 65 61 6c 20 65 70 | 69 6e 65 70 68 72 69 6e |cheal ep|inephrin|
|00001d90| 65 20 28 61 64 72 65 6e | 61 6c 69 6e 65 29 20 69 |e (adren|aline) i|
|00001da0| 6e 20 63 61 72 64 69 61 | 63 20 61 72 72 65 73 74 |n cardia|c arrest|
|00001db0| 20 77 61 73 0d 0a 71 75 | 65 73 74 69 6f 6e 65 64 | was..qu|estioned|
|00001dc0| 20 62 65 63 61 75 73 65 | 20 6f 66 20 61 20 6c 61 | because| of a la|
|00001dd0| 63 6b 20 6f 66 20 65 76 | 69 64 65 6e 63 65 20 74 |ck of ev|idence t|
|00001de0| 68 61 74 20 64 72 75 67 | 20 72 65 61 63 68 65 73 |hat drug| reaches|
|00001df0| 20 74 68 65 20 61 72 74 | 65 72 69 61 6c 0d 0a 63 | the art|erial..c|
|00001e00| 69 72 63 75 6c 61 74 69 | 6f 6e 2e 20 20 50 6c 61 |irculati|on. Pla|
|00001e10| 73 6d 61 20 65 70 69 6e | 65 70 68 72 69 6e 65 20 |sma epin|ephrine |
|00001e20| 6c 65 76 65 6c 73 20 77 | 65 72 65 20 63 6f 6d 70 |levels w|ere comp|
|00001e30| 61 72 65 64 20 61 66 74 | 65 72 20 69 6e 74 72 61 |ared aft|er intra|
|00001e40| 76 65 6e 6f 75 73 20 61 | 6e 64 0d 0a 65 6e 64 6f |venous a|nd..endo|
|00001e50| 74 72 61 63 68 65 61 6c | 20 61 64 6d 69 6e 69 73 |tracheal| adminis|
|00001e60| 74 72 61 74 69 6f 6e 20 | 69 6e 20 31 32 20 70 61 |tration |in 12 pa|
|00001e70| 74 69 65 6e 74 73 20 73 | 65 65 6e 20 69 6e 20 61 |tients s|een in a|
|00001e80| 6e 20 65 6d 65 72 67 65 | 6e 63 79 20 64 65 70 61 |n emerge|ncy depa|
|00001e90| 72 74 6d 65 6e 74 20 69 | 6e 0d 0a 61 73 79 73 74 |rtment i|n..asyst|
|00001ea0| 6f 6c 69 63 20 63 61 72 | 64 69 61 63 20 61 72 72 |olic car|diac arr|
|00001eb0| 65 73 74 2e 20 20 46 69 | 76 65 20 70 61 74 69 65 |est. Fi|ve patie|
|00001ec0| 6e 74 73 20 77 65 72 65 | 20 72 61 6e 64 6f 6d 6c |nts were| randoml|
|00001ed0| 79 20 61 73 73 69 67 6e | 65 64 20 74 6f 20 72 65 |y assign|ed to re|
|00001ee0| 63 65 69 76 65 0d 0a 65 | 70 69 6e 65 70 68 72 69 |ceive..e|pinephri|
|00001ef0| 6e 65 20 62 79 20 74 68 | 65 20 65 6e 64 6f 74 72 |ne by th|e endotr|
|00001f00| 61 63 68 65 61 6c 20 72 | 6f 75 74 65 20 61 6e 64 |acheal r|oute and|
|00001f10| 20 37 20 77 65 72 65 20 | 67 69 76 65 6e 20 31 20 | 7 were |given 1 |
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|00001f30| 0a 70 72 65 70 61 72 61 | 74 69 6f 6e 20 6f 66 20 |.prepara|tion of |
|00001f40| 65 70 69 6e 65 70 68 72 | 69 6e 65 20 69 6e 74 72 |epinephr|ine intr|
|00001f50| 61 76 65 6e 6f 75 73 6c | 79 2e 20 20 54 68 65 20 |avenousl|y. The |
|00001f60| 66 6f 72 6d 65 72 20 70 | 61 74 69 65 6e 74 73 20 |former p|atients |
|00001f70| 72 65 63 65 69 76 65 64 | 20 36 0d 0a 76 65 6e 74 |received| 6..vent|
|00001f80| 69 6c 61 74 69 6f 6e 73 | 20 61 66 74 65 72 20 69 |ilations| after i|
|00001f90| 6e 73 74 69 6c 6c 61 74 | 69 6f 6e 20 6f 66 20 31 |nstillat|ion of 1|
|00001fa0| 30 20 6d 6c 20 6f 66 20 | 31 3a 31 30 2c 30 30 30 |0 ml of |1:10,000|
|00001fb0| 20 65 70 69 6e 65 70 68 | 72 69 6e 65 20 69 6e 74 | epineph|rine int|
|00001fc0| 6f 20 74 68 65 0d 0a 65 | 6e 64 6f 74 72 61 63 68 |o the..e|ndotrach|
|00001fd0| 65 61 6c 20 74 75 62 65 | 2e 0d 0a 20 20 20 20 20 |eal tube|... |
|00001fe0| 41 20 67 6f 6f 64 20 63 | 6c 69 6e 69 63 61 6c 20 |A good c|linical |
|00001ff0| 61 6e 64 20 62 69 6f 63 | 68 65 6d 69 63 61 6c 20 |and bioc|hemical |
|00002000| 72 65 73 70 6f 6e 73 65 | 20 66 6f 6c 6c 6f 77 65 |response| followe|
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|00002030| 6e 20 6f 66 20 65 70 69 | 6e 65 70 68 72 69 6e 65 |n of epi|nephrine|
|00002040| 2c 20 62 75 74 20 74 68 | 65 72 65 20 77 61 73 20 |, but th|ere was |
|00002050| 6e 6f 20 61 70 70 61 72 | 65 6e 74 20 63 6c 69 6e |no appar|ent clin|
|00002060| 69 63 61 6c 20 72 65 73 | 70 6f 6e 73 65 20 61 6e |ical res|ponse an|
|00002070| 64 0d 0a 6e 6f 20 63 68 | 61 6e 67 65 20 69 6e 20 |d..no ch|ange in |
|00002080| 74 68 65 20 73 65 72 75 | 6d 20 65 70 69 6e 65 70 |the seru|m epinep|
|00002090| 68 72 69 6e 65 20 6c 65 | 76 65 6c 20 61 66 74 65 |hrine le|vel afte|
|000020a0| 72 20 65 6e 64 6f 74 72 | 61 63 68 65 61 6c 20 61 |r endotr|acheal a|
|000020b0| 64 6d 69 6e 69 73 74 72 | 61 74 69 6f 6e 2e 0d 0a |dministr|ation...|
|000020c0| 41 66 74 65 72 20 69 6e | 74 72 61 76 65 6e 6f 75 |After in|travenou|
|000020d0| 73 20 69 6e 6a 65 63 74 | 69 6f 6e 2c 20 65 70 69 |s inject|ion, epi|
|000020e0| 6e 65 70 68 72 69 6e 65 | 20 6c 65 76 65 6c 73 20 |nephrine| levels |
|000020f0| 72 6f 73 65 20 74 6f 20 | 6d 6f 72 65 20 74 68 61 |rose to |more tha|
|00002100| 6e 20 33 20 74 69 6d 65 | 73 20 74 68 65 0d 0a 69 |n 3 time|s the..i|
|00002110| 6e 69 74 69 61 6c 20 6c | 65 76 65 6c 20 77 69 74 |nitial l|evel wit|
|00002120| 68 69 6e 20 33 20 6d 69 | 6e 75 74 65 73 2e 20 20 |hin 3 mi|nutes. |
|00002130| 54 68 65 20 70 65 61 6b | 20 63 68 61 6e 67 65 20 |The peak| change |
|00002140| 69 6e 20 61 6e 79 20 70 | 61 74 69 65 6e 74 20 67 |in any p|atient g|
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|00002170| 20 77 61 73 20 32 38 20 | 70 6d 6f 6c 2f 6d 6c 2e | was 28 |pmol/ml.|
|00002180| 0d 0a 20 20 20 20 20 45 | 6e 64 6f 74 72 61 63 68 |.. E|ndotrach|
|00002190| 65 61 6c 20 61 64 6d 69 | 6e 69 73 74 72 61 74 69 |eal admi|nistrati|
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|00002200| 2e 0d 0a 0d 0a 50 6f 73 | 74 2d 43 6f 6d 6d 65 6e |.....Pos|t-Commen|
|00002210| 74 0d 0a 0d 0a 20 20 20 | 20 20 54 68 69 73 20 73 |t.... | This s|
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|00002230| 63 65 6e 74 20 6c 61 62 | 6f 72 61 74 6f 72 79 20 |cent lab|oratory |
|00002240| 64 61 74 61 20 66 72 6f | 6d 20 6f 75 72 20 6c 61 |data fro|m our la|
|00002250| 62 6f 72 61 74 6f 72 79 | 20 61 6e 64 20 66 72 6f |boratory| and fro|
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|00002280| 65 70 68 72 69 6e 65 20 | 69 73 20 6e 6f 74 20 77 |ephrine |is not w|
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|000023a0| 6f 74 68 65 72 0d 0a 70 | 6f 74 65 6e 74 69 61 6c |other..p|otential|
|000023b0| 20 66 61 63 74 6f 72 20 | 74 68 61 74 20 6f 6e 65 | factor |that one|
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|000023f0| 61 6c 6c 79 0d 0a 61 64 | 6d 69 6e 69 73 74 65 72 |ally..ad|minister|
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|00002430| 64 20 62 79 20 74 68 65 | 20 69 6e 74 72 61 76 65 |d by the| intrave|
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|000024e0| 6f 74 20 61 73 20 70 72 | 6f 6e 6f 75 6e 63 65 64 |ot as pr|onounced|
|000024f0| 2c 20 65 70 69 6e 65 70 | 68 72 69 6e 65 20 63 6f |, epinep|hrine co|
|00002500| 6e 74 69 6e 75 65 73 20 | 74 6f 20 62 65 20 61 62 |ntinues |to be ab|
|00002510| 73 6f 72 62 65 64 20 66 | 72 6f 6d 20 74 68 65 20 |sorbed f|rom the |
|00002520| 6c 75 6e 67 73 20 66 6f | 72 20 31 35 2d 32 30 0d |lungs fo|r 15-20.|
|00002530| 0a 6d 69 6e 75 74 65 73 | 2e 20 20 49 66 20 61 20 |.minutes|. If a |
|00002540| 70 61 74 69 65 6e 74 20 | 69 73 20 72 65 73 75 73 |patient |is resus|
|00002550| 63 69 74 61 74 65 64 2c | 20 74 68 65 72 65 20 6d |citated,| there m|
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|000025b0| 68 65 61 72 74 20 61 6e | 64 20 62 6c 6f 6f 64 20 |heart an|d blood |
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|000025d0| 20 74 68 61 6e 20 64 65 | 73 69 72 65 64 2e 0d 0a | than de|sired...|
|000025e0| 20 20 20 20 20 41 74 20 | 6f 6e 65 20 74 69 6d 65 | At |one time|
|000025f0| 20 77 65 20 77 65 72 65 | 20 76 65 72 79 20 73 74 | we were| very st|
|00002600| 72 6f 6e 67 20 6f 6e 20 | 65 6e 64 6f 74 72 61 63 |rong on |endotrac|
|00002610| 68 65 61 6c 20 65 70 69 | 6e 65 70 68 72 69 6e 65 |heal epi|nephrine|
|00002620| 2e 20 20 48 6f 77 65 76 | 65 72 2c 20 77 69 74 68 |. Howev|er, with|
|00002630| 0d 0a 63 6c 69 6e 69 63 | 61 6c 20 64 61 74 61 20 |..clinic|al data |
|00002640| 73 75 63 68 20 61 73 20 | 74 68 69 73 20 61 6e 64 |such as |this and|
|00002650| 20 6e 65 77 20 6c 61 62 | 6f 72 61 74 6f 72 79 20 | new lab|oratory |
|00002660| 64 61 74 61 2c 20 77 65 | 20 62 65 67 69 6e 20 74 |data, we| begin t|
|00002670| 6f 20 73 65 72 69 6f 75 | 73 6c 79 0d 0a 71 75 65 |o seriou|sly..que|
|00002680| 73 74 69 6f 6e 20 74 68 | 65 20 62 65 6e 65 66 69 |stion th|e benefi|
|00002690| 74 20 6f 66 20 74 68 69 | 73 20 61 70 70 72 6f 61 |t of thi|s approa|
|000026a0| 63 68 2e 2d 2d 57 2e 48 | 2e 20 53 70 69 76 65 79 |ch.--W.H|. Spivey|
|000026b0| 2c 20 4d 2e 44 2e 0d 0a | 24 55 6e 69 71 75 65 5f |, M.D...|$Unique_|
|000026c0| 49 44 7b 59 52 42 30 35 | 39 30 32 7d 0d 0a 24 54 |ID{YRB05|902}..$T|
|000026d0| 69 74 6c 65 7b 4f 78 79 | 67 65 6e 20 46 72 65 65 |itle{Oxy|gen Free|
|000026e0| 20 52 61 64 69 63 61 6c | 73 20 61 6e 64 20 4d 79 | Radical|s and My|
|000026f0| 6f 63 61 72 64 69 61 6c | 20 52 65 70 65 72 66 75 |ocardial| Reperfu|
|00002700| 73 69 6f 6e 20 49 6e 6a | 75 72 79 7d 0d 0a 24 41 |sion Inj|ury}..$A|
|00002710| 75 74 68 6f 72 7b 0d 0a | 44 61 72 74 2c 20 52 43 |uthor{..|Dart, RC|
|00002720| 0d 0a 53 61 6e 64 65 72 | 73 2c 20 41 42 7d 0d 0a |..Sander|s, AB}..|
|00002730| 24 41 66 66 69 6c 69 61 | 74 69 6f 6e 7b 55 6e 69 |$Affilia|tion{Uni|
|00002740| 76 20 6f 66 20 41 72 69 | 7a 6f 6e 61 7d 0d 0a 24 |v of Ari|zona}..$|
|00002750| 4a 6f 75 72 6e 61 6c 7b | 41 6e 6e 20 45 6d 65 72 |Journal{|Ann Emer|
|00002760| 67 20 4d 65 64 7d 0d 0a | 24 53 75 62 6a 65 63 74 |g Med}..|$Subject|
|00002770| 7b 4f 78 79 67 65 6e 20 | 66 72 65 65 20 72 61 64 |{Oxygen |free rad|
|00002780| 69 63 61 6c 73 20 61 6e | 64 20 6d 79 6f 63 61 72 |icals an|d myocar|
|00002790| 64 69 61 6c 20 72 65 70 | 65 72 66 75 73 69 6f 6e |dial rep|erfusion|
|000027a0| 20 69 6e 6a 75 72 79 3b | 0d 0a 4d 79 6f 63 61 72 | injury;|..Myocar|
|000027b0| 64 69 61 6c 20 72 65 70 | 65 72 66 75 73 69 6f 6e |dial rep|erfusion|
|000027c0| 20 69 6e 6a 75 72 79 20 | 61 6e 64 20 6f 78 79 67 | injury |and oxyg|
|000027d0| 65 6e 20 66 72 65 65 20 | 72 61 64 69 63 61 6c 73 |en free |radicals|
|000027e0| 7d 0d 0a 24 56 6f 6c 75 | 6d 65 7b 31 37 7d 0d 0a |}..$Volu|me{17}..|
|000027f0| 24 50 61 67 65 7b 35 33 | 2d 35 38 7d 0d 0a 24 44 |$Page{53|-58}..$D|
|00002800| 61 74 65 7b 4a 61 6e 75 | 61 72 79 20 31 39 38 38 |ate{Janu|ary 1988|
|00002810| 7d 0d 0a 24 59 42 56 6f | 6c 7b 31 39 38 39 20 59 |}..$YBVo|l{1989 Y|
|00002820| 65 61 72 20 42 6f 6f 6b | 20 6f 66 20 45 6d 65 72 |ear Book| of Emer|
|00002830| 67 65 6e 63 79 20 4d 65 | 64 69 63 69 6e 65 7d 0d |gency Me|dicine}.|
|00002840| 0a 24 43 68 61 70 74 65 | 72 7b 31 2d 33 7d 0d 0a |.$Chapte|r{1-3}..|
|00002850| 24 59 42 45 64 69 74 6f | 72 7b 44 72 2e 20 57 61 |$YBEdito|r{Dr. Wa|
|00002860| 67 6e 65 72 7d 0d 0a 24 | 54 61 62 6c 65 7b 54 61 |gner}..$|Table{Ta|
|00002870| 62 6c 65 20 4f 6d 69 74 | 74 65 64 7d 0d 0a 24 43 |ble Omit|ted}..$C|
|00002880| 6f 6d 6d 65 6e 74 61 74 | 6f 72 7b 57 2e 48 2e 20 |ommentat|or{W.H. |
|00002890| 53 70 69 76 65 79 2c 20 | 4d 2e 44 2e 7d 0d 0a 0d |Spivey, |M.D.}...|
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|00002960| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00002970| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00002980| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
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|00002a10| 4a 61 6e 75 61 72 79 20 | 31 39 38 38 0d 0a 2d 2d |January |1988..--|
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|00002a30| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00002a40| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00002a50| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00002a60| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 0d 0a |--------|------..|
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|00003690| 4a 2e 54 2e 20 4e 69 65 | 6d 61 6e 6e 2c 20 4d 2e |J.T. Nie|mann, M.|
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|00003780| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
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|00003870| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
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